hematopoietic progenitor cell meaning in English

定向造血干细胞,造血组细胞

Examples

Objective : flt - 3 ligand ( fins - like tyrosine kinase receptor - 3 ligand , fl ) was a recently described growth factor affecting early hematopoietic progenitor cells , that play a key role in the growth and differentiation of primitive hematopoietic cells . fl promotes the survival , proliferation , and differentiation of hematopoietic progenitors in synergy with other growth factors
Fms样酪氨酸激酶受体3配体( fms - liketyrosinekinasereceptor - 3ligand ， fl )是一种新近发现的、能够有效地刺激早期造血的细胞因子，可单独或联合其他细胞因子促进造血干细胞的增殖。
In contrast to murine studies , studies of human hscs have relied on a number of in vitro assays that identify cells with the capacity to generate hematopoietic progenitors in long - term culture and to differentiation into multiple hematopoietic lineages . recently , two elegant animal models that enable the in vivo measurement of human hscs marrow repopulating potential have been developed . one is the sheep in utero transplantation system in which human hematopoietic progenitor cells are transferred into the sheep fetus in utero before the development of the ovine immune system
早在80年代中期， zanjani等就利用胚胎期免疫系统发育不完善，将人的造血干细胞移植到妊娠中期胚羊腹腔内，成功地建立了人胎羊造血干细胞嵌合体移植模型，并以此实验模型作为体内检测人造血干细胞和人骨髓间充质干细胞多向分化潜能的方法。
Cd 14 * monocytes or bone marrow derived hematopoietic progenitor cells cultured with granulocyte - macrophage colony - stimulating factor ( gm - csf ) and il - 4 differentiate into efficient apc with morphology and cell surface molecule expression typical of immature dc . it was demonstrated that a variety of factors ( such as lps , tnf - a , il - 1 , monocyte - conditioned medium , and cd40 receptor cross - linking ) induce the maturation of immature dc to mature dc that are much more potent in activating t cells by increasing the expression of costimulatory molecules and cytokines , promoting the migration of dc to draining lymph nodes , and down - regulating the capacity of dc to capture and process antigen
在体外，外周血cd14 ~ +单核细胞和cd34 ~ +骨髓造血前体细胞在粒细胞-巨噬细胞集落刺激因子( granulocyte - macrophagecolony - stimulatingfactor , gm - csf )和il - 4的共同作用下可分化为未成熟dc ，未成熟dc具有强大的摄取和处理抗原的能力，但其抗原提呈能力较弱；未成熟dc在炎性细胞因浙江大竿俗士学位论文潜廷平子汐ilq ， yfax病原成分汐lpsx单核细胞条件培养液或cd40l等作用下可分化为成熟dc 。

hematopoietic progenitor cell meaning in English

Examples

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